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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T14907 | CCT251545 | Wnt/beta-catenin | |
CCT251545 is an potent and oral-bioavailable WNT signaling inhibitor(IC50 of 5 nM in 7dF3 cells). | |||
T22633 | CCT251545 analogue, Compound 51 | Others | |
CCT251545 analog is a potent and selective CDK8/19 inhibitor (IC50: 5.1 nM and 5.6 nM, respectively). Mediator complex-associated kinases CDK8 and CDK19 are involved in the regulation of multiple transcription pathways. ... |